Mounjaro Dose Schedule UK: Complete Titration Guide 2026
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Mounjaro (tirzepatide) is taken as a once-weekly injection, starting low and increasing gradually. This titration approach minimises side effects while your body adapts. Use the slider below to jump to any week and see your expected dose.
Mounjaro Dose Titration Schedule
| Weeks | Dose | Pen colour (UK) |
|---|---|---|
| 1–4 | 2.5mg | Grey |
| 5–8 | 5mg | Red |
| 9–12 | 7.5mg | Yellow |
| 13–16 | 10mg | Purple |
| 17–20 | 12.5mg | Orange |
| 21+ | 15mg | Teal/dark blue |
The 2.5mg starting dose is not a therapeutic weight loss dose — it's purely for tolerability. Therapeutic doses begin from 5mg. Your prescriber may keep you on any dose if it's working well and you're tolerating it, rather than automatically increasing you.
Do You Have to Reach 15mg?
No — 15mg is the maximum dose, not a mandatory target. Many patients achieve excellent results on 5mg, 7.5mg or 10mg. Increase only if your current dose is well-tolerated, you haven't yet reached your target, and there's no clinical reason to hold at your current level.
How to Inject
- Choose your site: abdomen (avoiding the navel), upper thigh, or upper arm. Rotate sites each week.
- Clean skin with an alcohol wipe and let it dry.
- Remove the base cap and needle cap.
- Press the pen firmly against skin, press the button, hold for at least 10 seconds until you hear two clicks.
- Dispose in a sharps bin — never household waste.
Inject on the same day each week, at any time of day, with or without food.
Storage
- Refrigerate at 2°C–8°C
- Can be kept at room temperature (up to 30°C) for up to 21 days if needed
- Keep away from direct light; never freeze
What If I Miss a Dose?
- 4 days (96 hours) or fewer since the missed dose was due: take it as soon as possible, then resume your normal weekly schedule
- More than 4 days: skip it, take your next dose on the usual day
- Never take two doses in the same week
Mounjaro Prices by Dose
| Dose | Cheapest UK price |
|---|---|
| 2.5mg | From £119.95 |
| 5mg | From £154 |
| 7.5mg | From £200 |
| 10mg | From £229 |
| 12.5mg | From £246 |
| 15mg | From £266 |
Prices vary between pharmacies. Use the MedEazy Mounjaro price comparison tool for live pricing across 50+ GPhC-regulated UK pharmacies.
Frequently Asked Questions
How long does it take to reach 15mg?
Following the standard schedule, 20 weeks (about 5 months). Your prescriber may extend time at any dose if needed for tolerability.
Can I speed up the titration?
No. The 4-week intervals aren't optional — increasing faster significantly raises the risk of severe side effects.
Can I inject in my arm?
Yes — the upper arm is one of three approved sites alongside the abdomen and upper thigh. Rotate sites weekly.